Eagle

Multiple Locus Association Mapping on a Genome-Wide Scale

An implementation of multiple-locus association mapping on a genome-wide scale. 'Eagle' can handle inbred and outbred study populations, populations of arbitrary unknown complexity, and data larger than the memory capacity of the computer. Since 'Eagle' is based on linear mixed models, it is best suited to the analysis of data on continuous traits. However, it can tolerate non-normal data. 'Eagle' reports, as its findings, the best set of snp in strongest association with a trait. For users unfamiliar with R, to perform an analysis, run 'OpenGUI()'. This opens a web browser to the menu-driven user interface for the input of data, and for performing genome-wide analysis.

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Description file content

Package
Eagle
Type
Package
Title
Multiple Locus Association Mapping on a Genome-Wide Scale
Version
2.1.0
Maintainer
Andrew George
Author
Andrew George [aut, cre], Joshua Bowden [ctb], Ryan Stephenson [ctb], Hyun Kang [ctb], Noah Zaitlen [ctb], Claire Wade [ctb], Andrew Kirby [ctb], David Heckerman [ctb], Mark Daly [ctb], Eleazar Eskin [ctb]
Description
An implementation of multiple-locus association mapping on a genome-wide scale. 'Eagle' can handle inbred and outbred study populations, populations of arbitrary unknown complexity, and data larger than the memory capacity of the computer. Since 'Eagle' is based on linear mixed models, it is best suited to the analysis of data on continuous traits. However, it can tolerate non-normal data. 'Eagle' reports, as its findings, the best set of snp in strongest association with a trait. For users unfamiliar with R, to perform an analysis, run 'OpenGUI()'. This opens a web browser to the menu-driven user interface for the input of data, and for performing genome-wide analysis.
License
GPL-3
Depends
R (>= 3.6), shinyFiles, ggplot2, ggthemes
Imports
R.utils, mmap, matrixcalc, shiny, shinythemes, shinyBS, shinyjs, stats, utils, parallel, data.table
LinkingTo
RcppEigen, Rcpp
LazyData
true
ByteCompile
TRUE
NeedsCompilation
yes
URL
Contact
eaglehelp@csiro.au
Packaged
2019-11-14 05:42:06 UTC; geo047
Repository
CRAN
Date/Publication
2019-11-14 06:20:10 UTC

install.packages('Eagle')

2.1.0

a day ago

http://eagle.r-forge.r-project.org

Andrew George

GPL-3

Depends on

R (>= 3.6), shinyFiles, ggplot2, ggthemes

Imports

R.utils, mmap, matrixcalc, shiny, shinythemes, shinyBS, shinyjs, stats, utils, parallel, data.table

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