EmpiricalCalibration

Routines for Performing Empirical Calibration of Observational Study Estimates

Routines for performing empirical calibration of observational study estimates. By using a set of negative control hypotheses we can estimate the empirical null distribution of a particular observational study setup. This empirical null distribution can be used to compute a calibrated p-value, which reflects the probability of observing an estimated effect size when the null hypothesis is true taking both random and systematic error into account. A similar approach can be used to calibrate confidence intervals, using both negative and positive controls.

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Description file content

Package
EmpiricalCalibration
Type
Package
Title
Routines for Performing Empirical Calibration of Observational Study Estimates
Version
2.0.0
Date
2019-07-08
Maintainer
Martijn Schuemie
Description
Routines for performing empirical calibration of observational study estimates. By using a set of negative control hypotheses we can estimate the empirical null distribution of a particular observational study setup. This empirical null distribution can be used to compute a calibrated p-value, which reflects the probability of observing an estimated effect size when the null hypothesis is true taking both random and systematic error into account. A similar approach can be used to calibrate confidence intervals, using both negative and positive controls.
VignetteBuilder
knitr
Imports
ggplot2 (>= 2.0.0), gridExtra, methods
Suggests
knitr, rmarkdown
License
Apache License 2.0
URL
BugReports
https://github.com/OHDSI/EmpiricalCalibration/issues
RoxygenNote
6.1.1
NeedsCompilation
no
Packaged
2019-07-08 12:34:23 UTC; mschuemi
Author
Martijn Schuemie [aut, cre], Marc Suchard [aut]
Repository
CRAN
Date/Publication
2019-07-08 15:30:03 UTC

install.packages('EmpiricalCalibration')

2.0.0

9 days ago

https://ohdsi.github.io/EmpiricalCalibration

Martijn Schuemie

Apache License 2.0

Imports

ggplot2 (>= 2.0.0), gridExtra, methods

Suggests

knitr, rmarkdown

Discussions