POD

Probability of Detection for Qualitative PCR Methods

This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' <http://quodata.de/>. The modelling itself has been described by Uhlig et al. (2015) <doi:10.1007/s00769-015-1112-9>.

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Description file content

Package
POD
Type
Package
Title
Probability of Detection for Qualitative PCR Methods
Version
1.1.4
Date
2019-06-11
Author
Markus Boenn (State Office for Consumer Protection Saxony-Anhalt, Germany)
Maintainer
Markus Boenn
Description
This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' . The modelling itself has been described by Uhlig et al. (2015) .
License
GPL-3
Encoding
UTF-8
LazyData
true
Depends
R (>= 3.4.0)
VignetteBuilder
knitr
RoxygenNote
6.1.1
NeedsCompilation
no
Packaged
2019-06-11 08:11:30 UTC; boenn
Repository
CRAN
Date/Publication
2019-06-11 08:20:02 UTC

install.packages('POD')

1.1.4

5 days ago

Markus Boenn

GPL-3

Depends on

R (>= 3.4.0)

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