PPMR

Probabilistic Two Sample Mendelian Randomization

Efficient statistical inference of two-sample MR (Mendelian Randomization) analysis. It can account for the correlated instruments and the horizontal pleiotropy, and can provide the accurate estimates of both causal effect and horizontal pleiotropy effect as well as the two corresponding p-values. There are two main functions in the 'PPMR' package. One is PMR_individual() for individual level data, the other is PMR_summary() for summary data.

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Description file content

Package
PPMR
Title
Probabilistic Two Sample Mendelian Randomization
Type
Package
Version
1.0
Description
Efficient statistical inference of two-sample MR (Mendelian Randomization) analysis. It can account for the correlated instruments and the horizontal pleiotropy, and can provide the accurate estimates of both causal effect and horizontal pleiotropy effect as well as the two corresponding p-values. There are two main functions in the 'PPMR' package. One is PMR_individual() for individual level data, the other is PMR_summary() for summary data.
License
GPL-3
Encoding
UTF-8
LazyData
true
Imports
Rcpp (>= 1.0.0)
LinkingTo
Rcpp, RcppArmadillo
RoxygenNote
6.1.1.9000
NeedsCompilation
yes
BugReports
https://github.com/umich-biostatistics/PPMR/issues
Packaged
2019-08-08 13:46:00 UTC; mkleinsa
Author
Zhongshang Yuan [aut], Xiang Zhou [aut], Michael Kleinsasser [cre]
Maintainer
Michael Kleinsasser
Depends
R (>= 3.5.0)
Repository
CRAN
Date/Publication
2019-08-09 10:20:07 UTC

install.packages('PPMR')

1.0

12 days ago

Michael Kleinsasser

GPL-3

Depends on

R (>= 3.5.0)

Imports

Rcpp (>= 1.0.0)

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