seqCBS

Copy Number Profiling using Sequencing and CBS

This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.

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Description file content

Package
seqCBS
Type
Package
Title
Copy Number Profiling using Sequencing and CBS
Version
1.2.1
Date
2019-04-12
Author
Jeremy J. Shen, Nancy R. Zhang
Maintainer
Jeremy J. Shen
Description
This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.
License
GPL-2
LazyLoad
yes
Depends
R (>= 2.10), clue
Repository
CRAN
NeedsCompilation
yes
Packaged
2019-04-13 04:52:17 UTC; jshen
Date/Publication
2019-04-13 05:22:55 UTC

install.packages('seqCBS')

1.2.1

11 days ago

Jeremy J. Shen

GPL-2

Depends on

R (>= 2.10), clue

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